Wednesday, October 17, 2018

t cell lymphoma survival rate | Prognosis and survival for non Hodgkin Lymphoma




Prognosis and survival for non Hodgkin Lymphoma





If you are diagnosed with lymphoma non Hodgkin (NHL), you may ask questions about your prognosis. A prognosis is the Act by which the doctor evaluates the better how cancer affects a person and how he will react to the treatment. The prognosis and survival depend on many factors. Only a doctor who knows your health history, the type of cancer you have, the stadium and the characteristics of the disease, selected treatments and response to treatment may examine all these data together with the statistics survival to a prognosis.

A prognostic factor is one aspect of cancer or characteristic of the person the doctor takes into account when it is a prognosis. A predictive factor influences how the cancer responds to a certain treatment. Often approached the prognostic and predictive factors together and they both play a role in the choice of the treatment plan and the establishment of the prognosis.

Revised international prognostic index
The revised international Prognostic Index (RIPI) is a more recent version of the international Prognostic Index (IPI) that has been developed to help determine the outcome of people with a type of NHL aggressive (rapidly changing).

RIPI is based on the treatments of all new drugs including rituximab (Rituxan). It helps doctors assign categories of risk to people with the number of adverse prognostic factors they present. RIPI has recourse to the same factors as the IPI, and it divides people into 3 categories of risk.

Age
Seniors 60 years of age tend to have a better prognosis than those who have more than 60 years.

Stadium
Low over the stadium of the NHL, the better the prognosis. The NHL stage 1 or 2 create a prognosis more favourable than the NHL from stage 3 or 4.

Rate of lacticodeshydrogenase (LDH)
A person whose blood levels of LDH is normal tends to have a better prognosis that a person whose rate of LDH is high. A higher than normal rate of LDH usually means that the cancer is more advanced. The rate of LDH is often higher among people with a type of NHL rapidly evolving.

Extranodal spread
When the NHL spreads to a body or to tissue outside the lymph nodes, we talk of extranodal spread. NHL which is only in the lymph nodes is more likely to be dealt with effectively and creates a better prognosis than an NHL that has spread beyond the lymph nodes.

Functional index
The functional index is the measure of the ability of a person to perform common tasks and daily activities. In general, the more a person is active and more she is able to carry out daily activities, best is the functional index. People whose functional index is good, either those that can operate almost normally, usually have a better prognosis than those whose performance status is low, i.e. those who need help in their activities daily or who must spend a lot of time in bed.

RIPI risk categories
Doctors assign the prognostic score based on RIPI. A point is allocated to each adverse prognostic factor. Down the more adverse prognostic factors, the better the prognosis.

A very good prognosis is related to no adverse prognostic factor.
A good prognosis is related to 1 or 2 adverse prognostic factors.
A prognosis is linked to 3 adverse prognostic factors or more.
Doctors use RIPI to identify cases of NHL who will probably react to the treatment and those who risk coming back (recurrence) after treatment.


Other prognostic factors
Doctors also take into consideration the following factors when evaluating the prognosis of the NHL.

Type of NHL
People with a B-cell lymphoma often have a better prognosis than those who are with lymphoma to T cells. 2 types of lymphocytes B the most frequent, follicular Lymphoma lymphomas generally creates a better prognosis than diffuse Lymphoma large cell B (DLBCL). Anaplastic large cell lymphoma, and Cutaneous Lymphoma T are 2 subtypes of lymphoma to t-cells that produce a fairly good prognosis.

Tumor volume
More the tumor is small, the better the prognosis. Small tumours tend to respond better to treatment. The large tumors often generate a less favourable prognosis. A very large tumour (10 cm or more) can be called a large tumor.

B symptoms
B symptoms include unexplained fever, important night sweats and unexplained weight loss. If B symptoms are present, the prognosis is less favorable.

Hemoglobin
A person with normal hemoglobin has a better prognosis that a person whose hemoglobin is low.

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